The French side moved to the brink of the Champions League quarter-finals with a ruthless 3-0 victory over Werder Bremen.
PSV goalkeeper Gomes misjudged a 25-metre free kick from Juninho as the Dutch side went down 0-1.
A spectacular goal by Jean Makoun gave Olympique Lyon a 1-0 win over Real Madrid in their Champions League last-16 first leg on Tuesday, handing the Spaniards their first away defeat in this season's competition. Lyon picked up their third successive home win over Real in the Champions League after the Cameroon midfielder drove a stunning 25-metre shot into the top corner of the net in the 47th minute.
Lyon sealed top spot in the Europa League standings while Roma survived a red-card scare to reach the last 16 on a chaotic final league-phase night.
AS Roma took a big step towards qualifying for the Europa League last 16 with a 2-0 win over VfB Stuttgart on Thursday.
Olympique Lyonnais are on the verge of signing Brazil defender Rafael from Manchester United, the French club's president said on Monday.
Lyon thump Maccabi Tel Aviv to go top, Forest keep on winning
Olympique Lyonnais coach Paulo Fonseca has been suspended for nine months by the French Professional Football League (LFP), following a confrontation with referee Benoit Millot.
Aston Villa secured a 2-1 victory at Basel on Thursday, with goals from Evann Guessand and Youri Tielemans keeping their Europa League campaign on a strong footing.
Olympique Lyon and Fenerbahce filled the last two Champions League knockout places after wins over Rangers and CSKA Moscow.
A summary of Thursday's Europa League quarter-finals second-leg.
Nottingham Forest, who finished seventh in the Premier League last season, will replace Palace in the Europa League.
Three Frenchmen, one a member of a far-right organisation, were held for questioning after allegedly assaulting Tottenham fans ahead of the London-based team's Europa League match against Olympique Lyon, police said on Thursday.
Nottingham Forest handed manager Sean Dyche the perfect debut with a 2-0 home win over Porto in the Europa League on Thursday, with both goals coming from the penalty spot.
A stoppage-time finish from Rayan Cherki earned Olympique Lyonnais a dramatic 2-2 draw with Manchester United in the first leg of their Europa League quarter-final.
Ligue 1 leaders Olympique Lyon lost 2-0 to Lille at the Stade de France on Saturday and saw their advantage at the top cut to just one point.
Olympique Lyon's hopes of clinching an eighth consecutive Ligue 1 title suffered another blow when they were held to a goalless draw at home to Paris St Germain on Friday.
Olympique Lyon lifted their first trophy in four years after Lisandro Lopez secured a hard-fought 1-0 win over gallant amateurs Quevilly in the French Cup final on Saturday.
Champions Olympique Lyon dented Olympique Marseille's chances of playing in Europe next season with a 1-0 away victory.
Olympique Lyon's Argentine striker Lisandro Lopez scored twice to help his side beat Girondins Bordeaux 3-1 in a lively first leg of the Champions League's first all-French quarter-final on Tuesday.
A 25-metre half-volley from Miohel Bastos helped Olympique Lyon defeat AS Nancy 3-1 to grab top spot in Ligue 1 on Saturday.
A late Bafetimbi Gomis goal gave Olympique Lyon a 2-1 home win over Toulouse to send the seven-times champions to the top of Ligue 1 on Saturday.
Argentine striker Lisandro Lopez is set to join Olympique Lyon from Porto, the Ligue 1 club said on Tuesday. The two sides had agreed a fee of 24 million euros ($33.48 million), Lyon said on their website (www.olweb.fr).
Olympique Lyon stayed on course for a seventh consecutive Ligue 1 title by winning 2-1 at mid-table Valenciennes on Sunday.
Manchester United suffered a setback as they were shocked by FC Copenhagen.
Olympique Lyon's miserable start to the Ligue 1 season continued with a 2-0 defeat at Girondins Bordeaux on Sunday.
Olympique Lyon wrapped up a record seventh consecutive Ligue 1 title with a convincing 3-1 win at AJ Auxerre.
Olympique Lyon suffered another setback when Lorient knocked them out of the French League Cup with a 1-0 home win on Wednesday.
APOEL Nicosia again ripped the Champions League record books to shreds and kicked off an island party by becoming the first Cypriot team to make the last eight of any European competition on Wednesday.
Manchester United manager Alex Ferguson will call on a rested Cristiano Ronaldo and Wayne Rooney to fire his side into the Champions League quarter-finals at the expense of Olympique Lyon on Tuesday. The tie with French champions Lyon is evenly poised, albeit with United having an away goal in the bank after a late Carlos Tevez strike secured United a 1-1 draw in Lyon last week.
Olympique Lyon midfielder Michael Essien appears set to stay with the club for now after talks between the French champions and Chelsea.
Olympique Lyon have agreed to let Mali midfielder Mahamadou Diarra join Real Madrid.
On debut, substitute Marcus Rashford became the first Englishman to play a first-team game for Barcelona since former England striker Gary Lineker in 1989.
French club Olympique Lyon and Atletico Madrid of Spain booked their places in Thursday's draw for the Champions League group stages with convincing playoff wins on Tuesday.
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